Term: Estimated Glomerular Filtration Rate (eGFR)

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Glossary Definition

Last Updated: 2015-12-03

Definition:

Estimated Glomerular Filtration Rate (eGFR) is a measurement used to assess kidney function. It estimates the flow rate of fluid filtered through the kidneys. Predictive models have been developed for the relationship between serum creatinine and eGFR. Creatinine is filtered from the blood by the kidneys, so decreased kidney function results in elevated serum creatinine levels (KDIGO, 2012).

This measure is calculated based on Serum Creatinine (SCr; test code 0214, mg/dL) found in the Diagnostic Services Manitoba (DSM) - Chemistry Data (** - see note below) and age (years) in adults, or Serum Creatinine and height (cm) in children. For more information on this measure, please see the Estimated Glomerular Filtration Rate (eGFR) technical definition and formulas in Chartier et al. (2015).

**NOTE: The term "Diagnostic Services Manitoba (DSM) - Chemistry data" was used in Chartier et al. 2015 prior to the name change to Shared Health Diagnostic Services.

Related concepts 

• Chronic Kidney Disease (CKD)
• Risk of Chronic Kidney Disease (CKD) Progression to End Stage Kidney Disease (ESKD) - Heat Map

Related terms 

• Kidney Failure Risk Equation (KFRE)
• Manitoba Pediatric Chronic Kidney Disease Registry
• Shared Health Diagnostic Services (SHDS) - Chemistry Data

References 

• Kidney Disease Improving Global Outcomes (KDIGO). KDIGO Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease. Accessed May 4, 2015. 2012. Available from. [Report] (View)

Term used in 

• Chartier M, Dart A, Tangri N, Komenda P, Walld R, Bogdanovic B, Burchill C, Koseva I, McGowan K-L, Rajotte L. Care of Manitobans Living with Chronic Kidney Disease. Winnipeg, MB: Manitoba Centre for Health Policy, 2015. [Report] [Summary] [Updates and Errata] [Additional Materials] (View)